Peer reviewed publications

Gramer M and Britton T. Antibody Production by a Hybridoma Cell Line at High Cell Density is Limited by Two Independent Mechanisms. Biotechnology and Bioengineering. 2002, 79(3); 277-283.

Gramer M, Maas J, Lieberman M. Use of hollow fiber systems for rapid and direct scale up of antibody production from hybridoma cell lines cultured in CL-1000 flasks using BD Cell MAb medium.  Cytotechnology Short Communication. 2003, 42:155-162.

Gramer M and Poeschl D. Comparison of cell growth in T-flasks, in micro hollow fiber bioreactors, and in an industrial scale hollow fiber bioreactor system. Cytotechnology. 2000, 34:111-119.

Gramer M and Maas J. Optimal NS0 Cell Growth in a Hollow Fiber Bioreactor Requires Increased Serum Concentration or a Cholesterol Supplement on the Cell Side of the Fiber. Biotechnol. Prog. 2003, 19(6): 1762-1766.

Gramer, M. J.; Poeschl, D. M.; Conroy, M. J.; Hammer, B.E. Effect of Harvesting Protocol on Performance of a Hollow Fiber Bioreactor. Biotechnol. Bioeng. 1999, 65, 334340.

Hirschel, M. D.; Gruenberg, M. L. An Automated Hollow Fiber System for the Large Scale Manufacture of Mammalian Cell Secreted Product. In Large Scale Cell Culture Technology; Lydersen, B. K., Ed.; Macmillan: New York, 1988; pp 113144.

Gramer, M. J.; Poeschl, D. M. Screening Tool for Hollow Fiber Bioreactor Process Development. Biotechnol. Prog.1998, 14, 203209.

Gramer, M. J.; Britton, T. L. Selection and Isolation of Cells for Optimal Growth in Hollow Fiber Bioreactors. Hybridoma 2000, 19, 407412.