HF Primer™

SMALL SCALE HOLLOW FIBER BIOREACTOR

  • High density cell culture: 5x1010 cells
  • Single-use cultureware includes:
    • 1.5m² hollow fiber cartridge
    • High-efficiency oxygenator
  • Linear scale-up to automated systems
  • Manual control
  • Easy set-up
HF Primer - Small Scale Hollow Fiber Bioreactor

Flexible Facilities: Fits in a standard CO2 incubator

APPLICATIONS

  • Ideal for:
    • <1g production of challenging proteins
    • Feasibility runs for C3’s automated
      hollow fiber sytems
  • Manufactures expressed proteins from mammalian and insect cell lines:
    • Monoclonal antibodies
    • Recombinant proteins
  • Supports adherent and suspension cells
Cells grow to a tissue-like density outside the hollow fibers to maximize production (EM photo of hollow fiber cross section)

Cells grow to a tissue-like density outside the hollow fibers to maximize production (EM photo of hollow fiber cross section)

FEATURES

  • Perfusion
  • Gas Exchange Cartridge
  • Continuous Harvest
  • No Passaging Required
  • Extended Runs (Weeks to Months)
  • Concentrated Harvest
  • Single-Use

BENEFITS

  • Supports high cell density for
    maximum productivity
  • Improves cell health compared to
    simplistic silicone tubing
  • Decreases labor, protects quality
  • Reduces labor
  • Flexible production schedules
  • Reduces downstream processing
  • Ready-to-Use, rapid turnaround

SPECIFICATIONS

  • Weight:
    • 0.9kg
  • Equipment/Requirements:
    • Peristaltic pump, 2 pump heads
      CO2, incubator
  • Dimensions (cm):
    • 12 W x 20 D x 33 H